Volume 6 (2022-2023)
Volume 5 (2021-2022)
Volume 4 (2020-2021)
Volume 3 (2019-2020)
Volume 2 (2018-2019)
Volume 1 (2017-2018)
Main Subjects = Biological sciences
Number of Articles: 10
The Golden Doses of Anti CD3/CD28 Microbeads Plus IL-15 Promote Expansion of Specific T Cells in Human Cytomegalovirus Adaptive Immunotherapy
Articles in Press, Accepted Manuscript, Available Online from 14 March 2023
Abstract
Background: There are various mechanisms are being developed to expand Virus specific T lymphocytes. In this study, the use of anti-CD3/CD28 magnetic microbeads and IL-15 in the culture of T lymphocytes in vitro has a significant role in the proliferation and cytotoxicity of these cells. Materials and ... Read MorePolyherbal formulation: An alternative therapeutic approach to treat diabetic foot ulcer
Volume 6, Issue 4 , March 2023, , Pages 1-13
Abstract
Diabetic Foot Ulcers (DFUs) are a common complication of poorly controlled diabetes and often become infected, termed diabetic foot infection. Despite using several multidisciplinary techniques, no significant cure is still achievable. So, it needs an alternative therapeutic approach to treat diabetic ... Read MoreInduction and evaluation of influenza cell-mediated immune responses by HA2 subunit and bio adjuvant as a gene vaccine candidate
Volume 6, Issue 4 , March 2023, , Pages 56-66
Abstract
The stalk domain of influenza as Hemagglutinin 2 (HA2) is a conserved unit of HA and is a candidate for a vaccine construct. We designed HA2/Mx (Myxovirus Resistance) as bio adjuvant construct for vaccine candidates. After immunization of Razi Balb/c mice in DNA/prime/boost strategy, for determination ... Read MoreWhole exome sequencing reveals the first c.7456C>T p.Arg2486X mutation in ATM gene in Iranian population
Volume 6, Issue 3 , December 2022, , Pages 57-72
Abstract
Mutations in Ataxia-Telangiectasia Mutated (ATM) gene are prominently responsible for the condition. ATM gene encodes a serine/threonine protein kinase, a crucial component in DNA repair systems. Whole exome sequencing was performed on a nine year old male subject with clinical features of A-T. Alpha ... Read MoreEctodermal Dysplasia patients susceptible to COVID-19
Volume 6, Issue 2 , September 2022, , Pages 78-80
Abstract
Ectodermal dysplasia (ED) is a rare heterogeneous disorder. Defects in the development of the ectoderm cause symptoms in tissues derived from the ectoderm layer such as skin, nails and hair. One of the genes involved in ED is Nuclear Factor Kappa-B (NF-κB) that mutation in this gene causes immunodeficiency. ... Read MoreBiotransformation of atropine, 4-hydroxy coumarin, 8-hydroxy quinoline, indole and penicillin G by the natural microflora
Volume 6, Issue 1 , June 2022, , Pages 13-25
Abstract
It has been found that natural microorganism have a siginificant role in the production and development of new medicines. The present study aimed to evaluat biotransformation of atropine, 4-hydroxy coumarin, 8-hydroxy quinoline, indole and industrially compound (penicillin G), arrive in the human body, ... Read MoreThe effect of Ajuga reptans extract on in vitro maturation of rat oocytes
Volume 6, Issue 1 , June 2022, , Pages 33-52
Abstract
Resumption of nuclear maturation and cytoplasmic changes occur during in vitro maturation. In vitro maturation of the egg provides a stage called Metaphase II (MII) that is required for in vitro fertilization. This study aimed to investigate the effect of replacing Follicle-Stimulating Hormone (FSH) ... Read MoreInflammation and Colorectal Cancer: The Bioinformatics Analysis of Multifunctional Role of Microbiota and Diet in Colorectal Cancer Development
Volume 5, Issue 4 , March 2022, , Pages 1-25
Abstract
Chronic inflammation in colorectal cancer can result in the progression of tumorigenesis. Inflammation in the colorectal part of the body can be affected by microbiota, as well as an individual diet. These two factors play a critical role in cancer types related to the colon and rectum. This inflammation ... Read MoreThe role of different genes in causing infection of ectodermal dysplasia patients: A systematic review
Volume 5, Issue 4 , March 2022, , Pages 86-104
Abstract
Ectodermal dysplasia (ED) is a genetic disorder which is characterized by deficient tissues from ectoderm and mesoderm. In this systematic review, two researchers searched keywords such as Ectodermal Dysplasia and Hypohidrotic Ectodermal Dysplasia (HED) in Medline (PubMed), Scopus, and Web of Science ... Read MoreAdjustment of expression of TUBB8, SOX9 and BCL2 genes in apoptosis and polycystic ovarian cancer
Volume 5, Issue 4 , March 2022, , Pages 105-154