Document Type : Hypothesis

Authors

1 Medical Research Laboratory IMS and SUM Hospital Siksha O Anusandhan Deemed to be University K8 Kalinga Nagar

2 Central Research Laboratory, Institute of Dental Sciences, Siksha ‘O’ Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar-751003, Odisha, INDIA

3 Advanced Center for Treatment, Research & Education in Cancer, Tata Memorial Center, Mumbai, India

4 Department of plastic, reconstructive and cosmetic surgery, IMS and SUM Hospital, Siksha ‘O’ Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar-751003, Odisha, India

5 Department of Otorhinolaryngology, IMS and SUM Hospital, Siksha ‘O’ Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar-751003, Odisha, INDIA

10.22034/hbb.2022.360830.1043

Abstract

Diabetic foot ulcers (DFUs) are a common complication of poorly controlled diabetes and often become infected, termed diabetic foot infection. Despite using several multidisciplinary techniques, no significant cure is still achievable. So, it needs an alternative therapeutic approach to treat diabetic foot ulcers. Moreover, with the advent of multidrug resistance bacteria, the effectiveness of broad-spectrum antibiotics to treat DFUs has become an uphill task. So, it becomes a primary concern to search for alternative highly effective nontoxic drugs/polyhedral formulations from plants to treat DFUs. Although a considerable amount of work has been reported on developing a herbal formulation to treat DFUs, no serious attempt has been made to combat DFUs infected with MDR strains. This article provides a review of possible plants and research pathways that can be used to formulate an effective and safe herbal formulation to treat DFUs.

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