Medicinal sciences
Ani Boghozian; Ali Choopani; Hamid Reza Shiran; Amirhossein Choopani; Nahid Ghaedamini
Abstract
The purpose of this study was to investigate the effect of Artemisia Ouchei on the liver enzymes of post -treatment with paracetamol. Artemisia was collected from Kashan area in Iran. The flower Essential Oil of this plant was extracted using a cloner device and the components of it were separated and ...
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The purpose of this study was to investigate the effect of Artemisia Ouchei on the liver enzymes of post -treatment with paracetamol. Artemisia was collected from Kashan area in Iran. The flower Essential Oil of this plant was extracted using a cloner device and the components of it were separated and identified using gas chromatography mass spectrometry. Four groups of animals were used to measure liver factors: 1- control, 2- paracetamol, 3- paracetamol with essential oil, 4- essential oil only. Paracetamol was injected for 3 days and essential oil for 7 days. ALP, AST, ALT were measured 3 days after the last blood transfusion. Essential oil with paracetamol significantly reduced AST and ALT levels and increased ALP level compared to paracetamol alone. Paracetamol and Artemisia Ouchei both caused liver damage by oxidative stress, but their combined use reduced their toxicity.