Document Type : Original Research Article

Abstract

Phytochemical investigation of the aerial parts of Artemisia kopetdaghensis led to isolation and characterization of 5 compounds including 9-Oxo-tournefortiolide (1), 2,6,10-Trimethyl-2,5-epidioxy-7,10-epoxydodeca-3,11-dien-5-acetoxy (2), 6-Demethoxy-5,7-dihydroxy-4'-O-methylcapillarisin (3), Eupatilin (4) and 5, 7, 5'-trihydroxy-6, 2´, 4´-trimethoxyflavone (5). The chemical structures of these compounds were identified by spectroscopic analysis. The antioxidant activities of the pure compounds were evaluated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays and also the antimicrobial capacity were tested against gram positive and gram negative bacteria and fungi using minimum inhibitory concentration (MIC) method.

Keywords

• Artemisia kopetdaghensis
• DPPH
• MIC