Carbon quantum dots may interfere with colorectal cancer treatment through affecting on glutamine metabolism

Mohadeseh Nemati; Fahima Danesh Pouya; Fateme Zarein; Mahdieh Nemati; Yousef Rasmi; Jafar Rezaie; Tooba Hallaj

Volume 6, Issue 2 , September 2022, Pages 1-5

  Cancer cells are metabolically different from normal cells, including the Warburg effect and uses glutamine to fill the Tricarboxylic Acid (TCA) cycle. It was demonstrated inhibiting glutamine metabolism prevents tumor growth. The mammalian Target of Rapamycin (mTOR) is one of the signaling pathways ...  Read More

Medicinal sciences
Investigating cellular and molecular factors effective in leukemia and analyzing the immune system

Nastaran Sahraei; Mina Mobin Rahni; Mehdi Ahmadifar

Volume 6, Issue 2 , September 2022, Pages 6-42

  Leukemia as one of the common cancers is still studied and needs improvement in diagnosis and treatment. In this study, we examined the activity of hematopoietic stem cells, which can be a precursor to leukemia. Hematopoietic cancer cells, by affecting the bone marrow, preserve the source of stem cells ...  Read More

Evaluation of ESR, CRP, LDH, CPK, D-Dimer, BS and FBS levels in hospitalized COVID-19 patients with mucormycosis

Seyed Hossein Shahcheraghi; Mahdie Hamidfar; Faezehsadat Heidari; Sajjad Shahmohammadi; Zohre Akhondimeybodi; Tahere Fallah; Yegane Aliakbarzade Yazdani

Volume 6, Issue 2 , September 2022, Pages 43-51

  Mucormycosis in COVID-19 patients of severe type has been reported. This study was intended to evaluate ESR, CRP, LDH, CPK, D-Dimer, BS and FBS levels in COVID-19 patients with mucormycosis. Information was recorded including gender, age, hospitalization and recovery. The laboratory parameters contained ...  Read More

Comparison of surgical site infection using active and passive surveillance methods in two months

Zohreh AkhoundiMeybodi; Mohammad Sharifyazdi; Reyhane Shaterian; bijan jafarnia; kazem ansari

Volume 6, Issue 2 , September 2022, Pages 52-63

  The aim of this study was to compare active and passive surveillance methods. This descriptive cross-sectional study was conducted on 296 patients who were admitted to Shahid Sadoughi hospital in Yazd from 2018 to 2020. Surveillance for signs of Surgical Site Infection (SSI) was done using passive (via ...  Read More

Antibiotic resistance pattern and frequency of SHV, CTX, TEM, and OXA resistance gene among salmonella serotypes

Maryam Naderi Mezajin; Mahdi Fatemizadeh; Zahra Rostami; Pejvak Khaki; Masoomeh Shirzad; Fatemeh Noorbakhsh

Volume 6, Issue 2 , September 2022, Pages 64-77

  The aim of this study was to investigate the antibiotic resistance and identification of strains producing broad-spectrum beta-lactamases salmonella strains. The 70 different strains of salmonella were studied that gentamicin, ciprofloxacin, ofloxacin, imipenem, and enrofloxacin were susceptible. The ...  Read More

Biological sciences
Ectodermal Dysplasia patients susceptible to COVID-19

Saeed Dorgaleleh; Karim naghipoor; Morteza Oladnabi

Volume 6, Issue 2 , September 2022, Pages 78-80

  Ectodermal dysplasia (ED) is a rare heterogeneous disorder. Defects in the development of the ectoderm cause symptoms in tissues derived from the ectoderm layer such as skin, nails and hair. One of the genes involved in ED is Nuclear Factor Kappa-B (NF-κB) that mutation in this gene causes immunodeficiency. ...  Read More