A role of telomerase in cancer progression and therapeutic program for anti-telomerase approach and future objectives
Volume 2, Issue 2 , October 2018, Pages 1-13


  Typically, the length of the telomeres is shortened at each time of cell division, which can induce chromosomal instability. In many tumor cells, telomere lengths are maintained by an enzyme called telomerase, which is a mechanism for starting and surviving tumors. The human telomerase reverse transcriptase ...  Read More

Plant antioxidants and their evaluation
Volume 2, Issue 2 , October 2018, Pages 14-18


  Antioxidants are substances at low concentrations and with a special mechanism which slow down or stop oxidation processes. Antioxidants are divided into two synthetic and natural categories. In this study, plants are the most important sources of antioxidants that could protect cells from oxidative ...  Read More

The survey of nosocomial infections in Yazd clinical settings during 2016
Volume 2, Issue 2 , October 2018, Pages 19-26


  In this study, we aimed to survey the health care in public hospitals in 2016 in three public hospitals in Yazd, since the level of hospital hygiene plays an important role in the incidence of nosocomial infections in patients admitted to hospital. The method of data collection was a form of the hygiene ...  Read More

A comparative study on microencapsulation of tryptophan synthase using Escherichia coli whole cells entrapped in different natural polymers
Volume 2, Issue 2 , October 2018, Pages 27-37


  Tryptophan (L-Trp) is a fundamental precursor to a number of drugs. In this research, three natural polymers included agar, agarose and alginate were investigated for immobilization of E. coli cells for L-Trp production to increase enzymatic stability. Also, the capability of beet molasses as serin (L-Ser) ...  Read More

Association of HLA-DRB1*1501-DQA1*0102-DQB1*0602 haplotype in patients with multiple sclerosis in Khuzestan province
Volume 2, Issue 2 , October 2018, Pages 38-48


  The aim of the present study was to reveal a part of genetic profile of multiple sclerosis (MS) in Khuzestan province. The contribution of HLA-DR2 haplotype (HLA-DRB1*1501-DQA1*0102-DQB1*0602) to MS risk is confirmed. This study included 187 MS patients and 192 healthy individuals. HLA alleles were genotyped, ...  Read More

Engineering plasmonic nanostructures with combining ultrasound and laser pulses
Volume 2, Issue 2 , October 2018, Pages 49-55


  The experimental conditions were investigated to fabricate Au nanorod (NRs) by pulsed laser ablation in water. This study revealed that it is possible to produce alternatively nanoparticles or nanorod at certain wavelengths depending on the laser. The values of the laser fluence for both wavelengths ...  Read More

The basic of bacterial resistance to antimicrobial drugs
Volume 2, Issue 2 , October 2018, Pages 56-68


  Drug-resistant organisms may have acquired resistance to first-line antibiotics, thereby obligating the use of second-line agents and so this problem is a serious and pre-eminent public health concern in the 21st century. Evolutionary pressure caused by misuse and overuse of antibiotics has played a ...  Read More