XylA, a signal peptide for periplasmic expression of human growth hormone in Escherichia coli
Volume 2, Issue 3 , December 2018, Pages 1-11


  Most of proteins produced in Escherichia coli accumulate as insoluble inclusion bodies. Optimal secretion of the recombinant protein can be obtained by a desirable signal peptide .In this research, we used Bacillus. sp endoxylanase signal peptide in order to guide the human growth hormone (HGH) to the ...  Read More

Evaluation of silver nanoparticles and alcoholic extract of Amaranthus retroflexus on pathogenic bacteria
Volume 2, Issue 3 , December 2018, Pages 12-23


  In recent years, application of medicinal plants increase in the treatment of infections rather than antimicrobial drugs. The aim of this study was to compare the effects of silver nanoparticles and alcoholic extract of Amaranthus retroflexus on some pathogenic bacteria. The alcoholic extract of this ...  Read More

Investigation of slow freezing of human testicular tissue on proliferation, colonization and viability of human spermatogonial stem cells
Volume 2, Issue 3 , December 2018, Pages 24-35


  In this study, the effects of freezing of testicular tissue by slow freezing on the proliferation rate, colonization and viability of spermatogonial stem cells (SSCs) were evaluated. The testicular tissue of the freezing group was freezed by slow-freezing method, and the fresh group remained intact. ...  Read More

Treatment of migraine headache with Migracorb, caffeine and ascorbic acid combination
Volume 2, Issue 3 , December 2018, Pages 36-47


  The migraine mechanism; the release of inflammatory neuropeptides, nuclear factor (NF-kB) and proinflammatory proteins leads to increase blood vessel permeability, tissue edema and pain sensitization. From 1989 to 2013 in a single blind randomized clinical trial conducted in Shiraz central hospital, ...  Read More

Assessing the frequency of t (12; 21) (p13; q22) in patients with acute lymphoblastic leukemia in northeastern of Iran
Volume 2, Issue 3 , December 2018, Pages 48-62


  Studying the results of the prevalence of a particular genetic translocation of acute lymphoblastic leukemia (ALL) could predict the incidence rate of overall survival (OS) and event-free survival (EFS). 283 patients from northeastern of Iran with new diagnosis of ALL by bone marrow aspiration or peripheral ...  Read More

Vitamin E reduces blood urea concentrations level after formaldehyde exposure in rat
Volume 2, Issue 3 , December 2018, Pages 63-67


  In this study, effect of vitamin E on kidney after exposure to formaldehyde was evaluated. 24 adult male wistar rats divided randomly in three groups: control, formaldehyde (E1), vitamin E and formaldehyde (E2). After two weeks rats were sacrificed, and 5 ml of blood was taken from their heart. Blood ...  Read More