Cytopenia in Influenza and possible treatment strategies (Drug and Vaccine)
Volume 3, Issue 3 , December 2019, Pages 1-11

  Viruses consistently present a major health danger and require a proper, balanced reaction from our immune system. Among viruses, human influenza viruses often cause morbidity and mortality, especially in populations at high risk. These viruses cause apoptosis in peripheral blood monocytes and tissue ...  Read More

A novel approach for analysis of shared genetic architecture of drug response based on summary statistics from genome-wide association studies
Volume 3, Issue 3 , December 2019, Pages 12-49

  The main objective of this study is to gain an exploratory sense of the relationships between the phenotypes (response to drugs) employing the genome‐wide association studies (GWAS) summary statistics for searching underlying contribution of pleiotropy across the associated SNPs to this relationship. ...  Read More

Importance of the catalytic site neighbouring residues on the functionality of the enzymes
Volume 3, Issue 3 , December 2019, Pages 50-58

  Catalytic residues are highly conserved among the proteins, amino acid residues which are sequentially neighbor to the catalytic sites, some extent contain similar structural information. Collected data from the Protein Data Bank (PDB) database contain one aspartic protease group (n=28) and two serine ...  Read More

Chemotherapy, dialysis and transplantation analysis among immunocompromised patients with focus on tuberculosis, syphilis, hepatitis B, C, HIV and chicken pox
Volume 3, Issue 3 , December 2019, Pages 59-68

  Immunodeficiency cases are a common cause of hospital deaths in hospitalized patients. Given the high prevalence of nosocomial deaths due to infection in immunocompromised patients, we aimed to evaluate Tuberculosis (TB), syphilis, hepatitis B and C, HIV and chickenpox in hospitalized immunocompromised ...  Read More

Frequency and antibiotic resistance pattern of the clinical isolates of extended spectrum beta Lactamase producing Escherichia coli from the blood specimens in hospitals and medical centers in Tabriz, Iran
Volume 3, Issue 3 , December 2019, Pages 69-78

  Production of Extended Spectrum Beta Lactamase (ESBL) enzymes is one of the main reasons for drug resistance in Escherichia coli (E. coli) isolates. The aim of this study was to determine the ESBL producing E. coli isolates in the blood culture of patients in hospitals and medical centers in Tabriz, ...  Read More

Fabrication of ketoconazole nanosuspention, by pearl milling technique and evaluation, characterization of nanocrystals prepared
Volume 3, Issue 3 , December 2019, Pages 79-89

  In the present study, ketoconazole nanosuspentoin were prepared in order to increase solubility by pearl milling technique via solution include Tween 60 and polyvinylpyrrolidone K30 (PVP K30). The Ketoconazole and the resulting ketoconazole nanosuspention were characterized by Fourier-Transform InfraRed ...  Read More