This study aimed to determine the effect of Ambon banana fruit consumption on plasma malondialdehyde (MDA) levels and other cardiometabolic indicators in adult men with central obesity. A total of 30 volunteers were involved. The volunteers were examined for their plasma MDA levels and cardiometabolic indicators before and after treatment. The results showed that consuming Ambon banana fruit at breakfast for 28 days significantly reduced body weight, BMI, waist circumference, and systolic and diastolic blood pressure (p<0.05). Consuming Ambon banana at breakfast for 28 days improved cardiometabolic indicators and reduced plasma MDA levels in men with central obesity.