Document Type : Opinion

Authors

1 1Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.

2 Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.

3 Department of pathology,school of medicine Imam Hossein Hospital

10.22034/hbb.2022.347020.1032

Abstract

Background: The emergence of nosocomial infection due to Multi Drug Resistant (MDR) bacteria is a challenge to infection control. Methods: This study was presented two Providencia species from two hospitalized patients admitted in Imam Hussein hospital, Iran. Biochemical and molecular tests were performed for identification of the strains. The resistance pattern of these isolates was determined using antimicrobial susceptibility test. The presence of the resistant genes was determined using PCR method. The presence of transmissible element was detected using conjugative test. Results: Both P. stuartii isolates were resistant to all antibiotics. Among carbapenemase resistance genes, blaNDM, blaGES and blaKPC were detected in both of them. One isolate was able to transfer the resistant gene in conjugation test. Conclusion: The presence of MDR strains among nosocomial infection agents such as P. stuartii isolates could affect the health care system efficiency.

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