Document Type : Review Article

Authors

1 Universitas Indonesia

2 Faculty of Medicine Universitas Indonesia, Jl. Salemba 6 jakarta pusat

10.22034/hbb.2022.353400.1038

Abstract

The development of tissue engineering provides various opportunities to engineer various tissues/organs, including vascular tissue engineering. Scaffold plays an essential role in vascular tissue engineering. The selection of biomaterials used as scaffolds will determine the success of vascular tissue engineering. The structure of vascular system, which consists of three layers, is embedded in extracellular matrices that provide the mechanical properties of the system. Therefore, tissue engineering of a vascular structure needs various suitable biomaterials as scaffold that can support vascular system mechanical properties and function.
Various materials were used for 3D printing and electro-spinning with good results, including collagen, gelatin, and alginate. In conclusion, the varying sizes of blood vessels require scaffolds with biomaterials that can adapt to their shape, size and approximate the mechanical properties of the blood vessels. Various biomaterials are suitable to produce scaffolds for vascular engineering.

Keywords