Document Type : Original Research Article


1 Department of Microbiology, Varamin-Pishva Branch, Islamic Azad Univercity, Varamin-Pishva, Iran

2 Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran

3 Department of Microbiology, Islamic Azad University Science and Research Branch , Islamic Azad Univercity, Tehran, Iran

4 Department of Microbiology, Razi Vaccine and serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran

5 Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran

6 Department of Microbiology, Biological Science College, Varamin-Pishva Branch, Islamic Azad Univercity, Varamin-Pishva, Iran



The aim of this study was to investigate the antibiotic resistance and identification of strains producing broad-spectrum beta-lactamases salmonella strains. The 70 different strains of salmonella were studied that gentamicin, ciprofloxacin, ofloxacin, imipenem, and enrofloxacin were susceptible. The highest resistance to cephalexin (96 %), cefazolin (96 %), cephalothin (65 %), and 69 isolates (98 %), were resistant to more than one antibiotic. The results of the Polymerase Chain Reaction (PCR) were evaluated on ESBL producing isolates using specific primers; in order to investigate the presence of CTX-Mbla, SHVbla, TEMbla and OXAbla, so the presence of germ cell resistance genes in total indicated that 32 isolates (56 %), at least one of the above genes.