Certain principles from the Holy Quran can enable scientists to follow human ethics about medicinal plants. In this research, we used references such as the Noble Quran, "Al-Mizan and Nemone" interpretations and Islamic jurisprudence books such as Wasayel-al-Shia. Some Quranic verses include definitions like" the source of admonition, happiness and rejoicing" furthermore, one of the important goals is to consider the wisdom of God. Empirical experiments indicated that plants also possess a high level of understanding of their condition. In the Quran, the plants such as Punica granatum L ،Zingiber officinale L، Vitis vinifera L and Phoenix dactylifera L, which are used in traditional medicine, are important. From the perspective of Islamic philosophy, plants are capable to benefit people in various ways, by perception, consciousness and emotions and Islamic law does not allow humans to destroy plants. And also articles that indexed in Scopus, PubMed, ISI and Google scholar.