Antibiotic resistance pattern and frequency of SHV, CTX, TEM, and OXA resistance gene among salmonella serotypes

Maryam Naderi Mezajin; Mahdi Fatemizadeh; Zahra Rostami; Pejvak Khaki; Masoomeh Shirzad; Fatemeh Noorbakhsh

Volume 6, Issue 2 , September 2022, , Pages 64-77

https://doi.org/10.22034/HBB.2022.17

Abstract
  The aim of this study was to investigate the antibiotic resistance and identification of strains producing broad-spectrum beta-lactamases salmonella strains. The 70 different strains of salmonella were studied that gentamicin, ciprofloxacin, ofloxacin, imipenem, and enrofloxacin were susceptible. The ...  Read More

Phytoconstituents and biological activities of Artemisia kopetdaghensis
Volume 1, Issue 3 , December 2017, , Pages 65-76

https://doi.org/10.22034/HBB.2017.19

Abstract
  Phytochemical investigation of the aerial parts of Artemisia kopetdaghensis led to isolation and characterization of 5 compounds including 9-Oxo-tournefortiolide (1), 2,6,10-Trimethyl-2,5-epidioxy-7,10-epoxydodeca-3,11-dien-5-acetoxy (2), 6-Demethoxy-5,7-dihydroxy-4'-O-methylcapillarisin (3), Eupatilin ...  Read More

Bioinformatics progress in Iran
Volume 1, Issue 4 , March 2018, , Pages 66-71

https://doi.org/10.22034/HBB.2018.06

Abstract
  Bioinformatics students should recognize their situation to their world. Today, we have a huge amount of publically available data that are yet to be analyzed. There is a big gap between the analyzed and well-understood data and the raw data. A bioinformatics researcher can play an important role ...  Read More

Biological sciences
Genotyping of KELL blood group in multiethnic populations of Quetta, Pakistan

Asifa Bibi; Nabeela Tariq; Hamida Ali; Zil-e-Huma Butt; Tasleem Kausar; Maqsood Maryam

Volume 7, Issue 2 , September 2023, , Pages 66-81

https://doi.org/10.22034/HBB.2023.18

Abstract
  KEL1 (Kell or K) is highly immunogenic with limited distribution while KEL2 (Cellano or k) antigen is more prevalent. The antigenic diversity in the Kell gene is a result of Single Nucleotide Polymorphisms (SNPs). Blood samples of 160 males and females from each ethnic group with no age restrictions ...  Read More

Determination of CAPN11 and UBQLN3 gene expression in men with Non-Obstructive Azoospermia

Masoud Salehipour; Masoumeh Karimi

Volume 6, Issue 4 , March 2023, , Pages 67-80

https://doi.org/10.22034/HBB.2023.06

Abstract
  Genetic disorders play an important role in male infertility, especially in Non-Obstructive Azoospermia (NOA). Many studies have been performed on the expression profiles of gonadal genes in order to accurately identify the genes involved in impaired spermatogenesis. In the current study, testicular ...  Read More

Insights into the evolutionary origin of Mycoplasma species
Volume 4, Issue 1 , June 2020, , Pages 68-85

https://doi.org/10.22034/HBB.2020.06

Abstract
  Mycoplasma species are cell wall deficient intracellular microorganisms that are related to respiratory and urogenital infections in human being. In this study, we are providing insights into the Mycoplasma evolutionary origin based on the taxonomical characterization of such microorganism and also searching ...  Read More

Frequency and antibiotic resistance pattern of the clinical isolates of extended spectrum beta Lactamase producing Escherichia coli from the blood specimens in hospitals and medical centers in Tabriz, Iran
Volume 3, Issue 3 , December 2019, , Pages 69-78

https://doi.org/10.22034/HBB.2019.24

Abstract
  Production of Extended Spectrum Beta Lactamase (ESBL) enzymes is one of the main reasons for drug resistance in Escherichia coli (E. coli) isolates. The aim of this study was to determine the ESBL producing E. coli isolates in the blood culture of patients in hospitals and medical centers in Tabriz, ...  Read More

Siger rice made from cassava (waxy) as rice which is recommended for diabetics
Volume 4, Issue 2 , September 2020, , Pages 70-79

https://doi.org/10.22034/HBB.2020.11

Abstract
  Siger rice has a very high amylose. The high amylose in Siger rice caused the amylose came out from the starch granules during the cooking process and release the water when it was cold until the rice became hard. This research aimed to measure the content of Siger rice from sticky cassava, using a single ...  Read More

The effect of Glycirrhiza globra on osteoarthritis, suppress TNF-a, IL-1b, Cox-2, iNOS gene expression and prostaglandin E2 and nitric oxide production in particular chondrocytes and monocyte/macrophages
Volume 1, Issue 2 , September 2017, , Pages 70-82

https://doi.org/10.22034/HBB.2017.13

Abstract
  In this study, we evaluated the effects of avocado soybean unsaponifiables (Glycirrhiza globra) on proinflammatory mediators in chondrocytes and monocyte/macrophage-like cells. Cells were activated with 20 ng/ml lipopolysaccharide (LPS) for 24 h and cell supernatants were analyzed for prostaglandin E2 ...  Read More

Prelevence of Salmonella typhi and pharmacotherapy outcomes among children in ten years in Hilla city, Iraq
Volume 3, Issue 4 , March 2020, , Pages 72-77

https://doi.org/10.22034/HBB.2020.31

Abstract
  Typhoid fever diseases menace the human health worldwide. This study assessed the prevalence of typhoid fever among children in Hilla City. A total of 217 samples were collected. Children were diagnosed with payrexia caused by S. typhi by records of medical used for statistical study tools considered. ...  Read More

Aqueous extract of Nigella sativa L suppress proinflamatory cytokine gene expression
Volume 1, Issue 4 , March 2018, , Pages 72-82

https://doi.org/10.22034/HBB.2018.07

Abstract
  Due to the side effects of current therapies for osteoarthritis one of the alternative medicine is using herbal medicine such as Nigella sativa L. We examined that alcoholic extract of Nigella sativa (AENS) has an anti-inflammatory activity. Cells were activated with 100 ng/ml lipopolysaccharide for ...  Read More

Plants rights foundation from Islamic perspective
Volume 1, Issue 1 , June 2017, , Pages 72-81

https://doi.org/10.22034/HBB.2017.07

Abstract
  Certain principles from the Holy Quran can enable scientists to follow human ethics about medicinal plants. In this research, we used references such as the Noble Quran, "Al-Mizan and Nemone" interpretations and Islamic jurisprudence books such as Wasayel-al-Shia. Some Quranic verses include definitions ...  Read More

Strategies in design of antibodies for cancer treatment
Volume 5, Issue 3 , December 2021, , Pages 72-96

https://doi.org/10.22034/HBB.2021.24

Abstract
  Structural bioinformatics and computational methodologies facilitate antibodies design. The rational design is used to achieve a new function or adopt a new structure. Computer algorithms can systematically search amino acid sequences and select the best one. One of the important points of protein therapeutics ...  Read More

Medicinal sciences
Isolation of MDR Providencia stuartii from tracheal aspirates of two hospitalized patients

Niloofar Rezaie; Shadi Agghamohammad; Mahdi Rohani; Abdolreza Javadi; Farzad Badmasti; Armaghan Soltani Shirazi

Volume 6, Issue 3 , December 2022, , Pages 73-79

https://doi.org/10.22034/HBB.2022.24

Abstract
  The emergence of nosocomial infection due to Multi-Drug Resistant (MDR) bacteria is a challenge to infection control. This study presented two Providencia species from two hospitalized patients admitted to Imam Hussein hospital in Iran. Biochemical and molecular tests were performed for the identification ...  Read More

Effectiveness of acceptance and commitment group therapy on quality of life and physical symptoms in gastrointestinal cancer patients
Volume 3, Issue 2 , September 2019, , Pages 74-82

https://doi.org/10.22034/HBB.2019.19

Abstract
  The aim of this study was to evaluate the effectiveness of acceptance and commitment group therapy on quality of life and physical symptoms in gastro-intestinal cancer patients. The research was quasi-experimental with pretest, posttest and control group. The statistical population included 32 men with ...  Read More

PEG derivatives, a new platform technology for pharmaceutical research in drug delivery
Volume 1, Issue 3 , December 2017, , Pages 77-80

https://doi.org/10.22034/HBB.2017.20

Abstract
  Methoxy polyethylene glycol (mPEG) with high molecular weight which has been used as a coating agent in drug delivery systems leads to more therapeutic efficacy. This supports the hypothesis that coating the drugs with higher molecular weight of PEG derivatives. The coating agent, methoxy polyethylene ...  Read More

Biological sciences
Investigating the association between Toll-Like Receptor 9 (TLR9) rs352139 genetic variants and Systemic Lupus Erythematosus (SLE) in an Iranian population

Mahdi Zarei; Mohsen Soroush; Saeed Mohammadi

Volume 7, Issue 3 , December 2023, , Pages 77-91

https://doi.org/10.22034/HBB.2023.25

Abstract
  Numerous studies have examined the effect of genetic variations in the Toll-Like Receptor 9 (TLR9) on the development of Systemic Lupus Erythematosus (SLE). An allele-specific PCR technique was employed to analyze the genetic variation in the study participants in a cohort of SLE and healthy controls ...  Read More

Biological sciences
Ectodermal Dysplasia patients susceptible to COVID-19

Saeed Dorgaleleh; Karim naghipoor; Morteza Oladnabi

Volume 6, Issue 2 , September 2022, , Pages 78-80

https://doi.org/10.22034/HBB.2022.18

Abstract
  Ectodermal dysplasia (ED) is a rare heterogeneous disorder. Defects in the development of the ectoderm cause symptoms in tissues derived from the ectoderm layer such as skin, nails and hair. One of the genes involved in ED is Nuclear Factor Kappa-B (NF-κB) that mutation in this gene causes immunodeficiency. ...  Read More

Medicinal sciences
Daily consumption of Ambon banana (Musa paradisiaca var. sapientum) improve cardiometabolic indicators and reduce plasma MDA levels in adult male with central obesity

Khairun Nisa; Dewi Nur Fiana; Liana Sidharti

Volume 7, Issue 1 , July 2023, , Pages 78-89

https://doi.org/10.22034/HBB.2023.12

Abstract
  This study aimed to determine the effect of Ambon banana fruit consumption on plasma malondialdehyde (MDA) levels and other cardiometabolic indicators in adult men with central obesity. A total of 30 volunteers were involved. The volunteers were examined for their plasma MDA levels and cardiometabolic ...  Read More

Fabrication of ketoconazole nanosuspention, by pearl milling technique and evaluation, characterization of nanocrystals prepared
Volume 3, Issue 3 , December 2019, , Pages 79-89

https://doi.org/10.22034/HBB.2019.25

Abstract
  In the present study, ketoconazole nanosuspentoin were prepared in order to increase solubility by pearl milling technique via solution include Tween 60 and polyvinylpyrrolidone K30 (PVP K30). The Ketoconazole and the resulting ketoconazole nanosuspention were characterized by Fourier-Transform InfraRed ...  Read More

Current scenario of nutraceuticals and food fortification in India
Volume 4, Issue 2 , September 2020, , Pages 80-89

https://doi.org/10.22034/HBB.2020.12

Abstract
  As nowadays the consumption of functional food providing essential nutrients for boosting the immunity should be correlated with scientific evidence providing standards that can be correlated for the community worldwide. Food fortification is a process which helps to improve public health and enhance ...  Read More

One pot, green synthesis and biological evaluation of some isatin-based thiocarbohydrazones derivatives

Seyyed Mohammad Shahcheragh; Azizollah Habibi; Masoomeh Shirzad; Yekta Farahani; Soroush Sardari

Volume 6, Issue 4 , March 2023, , Pages 81-97

https://doi.org/10.22034/HBB.2023.07

Abstract
  In the present study, a one-pot, green and three-component route for synthesis of Thiocarbohydrazone (TCS) derivatives is described. This reaction was performed in choline chloride/urea (1:2) as Deep Eutectic Solvent (DES). The structures were characterized by FTIR, 1H NMR, 13C NMR spectra and elemental ...  Read More

Biological sciences
Biofilm formation and drug resistance determinants of Moraxella catarrhalis, Moraxella osloensis and Moraxella lacunata from clinical samples in Iraq

Manal Hadi Ghaffoori Kanaan; Hiba Riyadh Al-abodi; Sura Saad Abdullah; Mojtaba Memariani; Maryam Kohansal; Abdolmajid Ghasemian

Volume 7, Issue 4 , March 2024, , Pages 81-97

https://doi.org/10.22034/HBB.2024.05

Abstract
  In this study, fifty Moraxella species were isolated. The antibiotic susceptibility, β-lactamases and minimum inhibitory and bactericidal concentrations were evaluated. The rate of ESBLs among M. catarrhalis, M. osloensis and M. lacunata included 47 % (n=11), 36.84 % (n=7) and 37.5 % (n=3), respectively. ...  Read More

Pharmaceutical sciences
Increased risk of cerebral dysfunction by high-fructose diet consumption: A 90 -day study in female rats

Roya Mirzaei; Sepideh Arbabi Bidgoli; Roya Khosrokhavar; Shahram Shoeibi; Hamidreza Ahmadi Ashtiani

Volume 7, Issue 2 , September 2023, , Pages 82-100

https://doi.org/10.22034/HBB.2023.19

Abstract
  Our study was designed to evaluate any changes in the liver, kidney, and brain tissues of female wistar rats to a fructose-enriched diet. Rats were divided into three groups (n=5/group). Monitoring of daily water-food consumption and clinical changes continued for 90 days. Afterward, the alteration of ...  Read More

Biological sciences
The role of different genes in causing infection of ectodermal dysplasia patients: A systematic review

Saeed Dorgaleleh; Zahra Toutounchi; Mahsa Soltani; Karim naghipoor; Morteza Oladnabi

Volume 5, Issue 4 , March 2022, , Pages 86-104

https://doi.org/10.22034/HBB.2022.05

Abstract
  Ectodermal dysplasia (ED) is a genetic disorder which is characterized by deficient tissues from ectoderm and mesoderm. In this systematic review, two researchers searched keywords such as Ectodermal Dysplasia and Hypohidrotic Ectodermal Dysplasia (HED) in Medline (PubMed), Scopus, and Web of Science ...  Read More