Revealing metabolic performance of chinese hamster ovary cell capable of producing erythropoietin by in silico analysis
Articles in Press, Accepted Manuscript, Available Online from 18 February 2023

https://doi.org/10.22034/hbb.2023.166944

Abstract
  Erythropoietin (EPO) is one of the most important hormones in the human body that plays a critical role in preventing cellular damage caused by hypoxia. Due to its effective pharmaceutical performance, recombinant human EPO (rhEPO) is often produced by Chinese Hamster Ovary (CHO) cells as host cells ...  Read More

Medicinal sciences
Daily Consumption of Ambon Banana (Musa paradisiaca var. Sapientum) Improve Cardiometabolic Indicators and Reduce Plasma MDA Levels in Adult Male with Central Obesity

Khairun Nisa; Dewi Nur Fiana; Liana Sidharti

Articles in Press, Accepted Manuscript, Available Online from 27 February 2023

https://doi.org/10.22034/hbb.2023.369184.1062

Abstract
  This study aimed to determine the effect of Ambon banana fruit consumption on plasma MDA levels and other cardiometabolic indicators in adult men with central obesity. A total of 30 volunteers were involved. The volunteers ask to take 250 grams of Ambon banana for breakfast for 28 days. The volunteers ...  Read More

Biological sciences
The Golden Doses of Anti CD3/CD28 Microbeads Plus IL-15 Promote Expansion of Specific T Cells in Human Cytomegalovirus Adaptive Immunotherapy

Arsalan Jalili; Nasser Aghdami; Abbas Hajifathali; Maryam Sayahinouri

Articles in Press, Accepted Manuscript, Available Online from 14 March 2023

https://doi.org/10.22034/hbb.2023.386576.1075

Abstract
  Background: There are various mechanisms are being developed to expand Virus specific T lymphocytes. In this study, the use of anti-CD3/CD28 magnetic microbeads and IL-15 in the culture of T lymphocytes in vitro has a significant role in the proliferation and cytotoxicity of these cells. Materials and ...  Read More

Medicinal sciences
The comparison and analysis among clinical studies of tissue engineering in knee cartilage defect

Ria Andreinie; Jeanne Adiwinata Adiwinata Pawitan

Articles in Press, Accepted Manuscript, Available Online from 24 April 2023

https://doi.org/10.22034/hbb.2023.377761.1068

Abstract
  Treatment of cartilage damage is not satisfactory mainly due to cartilage nature that is avascular, so that its nutrition only depends on the diffusion process, which does not support regeneration. One of the new approaches for regeneration of injured cartilage that have a future is tissue engineering. ...  Read More

Pharmaceutical sciences
Investigating the Protective Effect of the Methanolic Extract of Salvia multicaulis on Renal Ischemia-reperfusion Injuries in Rats

Foroogh Mirzania; Iraj Salimikia; Javad Ghasemian-Yadegari; Javid Aalaei; Mohammad Amin Ghobadi; Majid Taheri Demneh; Alireza Nazarzadeh

Articles in Press, Accepted Manuscript, Available Online from 06 May 2023

https://doi.org/10.22034/hbb.2023.382387.1073

Abstract
  In this research the protective effects of the methanolic extract of S. multicaulis was evaluated in renal ischaemia-reperfusion injuries in rats. 42 male rats were divided into 6 groups. In the treatment groups 1-3, before causing ischemia in the kidneys, rats received 50, 100, and 150 mg/kg/day doses ...  Read More

Medicinal sciences
Determining the characteristics of cerebral metastasis from breast cancer

Reza Nafisi Moghadam; Mojtaba Jokar; Shima sadat Dehghanpour farashah; Alirezaa Zolfagharii

Articles in Press, Accepted Manuscript, Available Online from 08 May 2023

https://doi.org/10.22034/hbb.2023.370318.1064

Abstract
  Breast cancer is the most malignancy in women. The aim of this study was to evaluate determining the characteristics of cerebral metastasis from breast cancer. This cross sectional study was conducted on patients with cerebral metastasis from breast cancer in Shahid Sadoughi hospital from 2014 to 2020 ...  Read More