%0 Journal Article %T Vitamin E reduces blood urea concentrations level after formaldehyde exposure in rat %J Health Biotechnology and Biopharma (HBB) %I Health Biotechnology and Biopharma %Z 2538-4414 %D 2018 %\ 12/01/2018 %V 2 %N 3 %P 63-67 %! Vitamin E reduces blood urea concentrations level after formaldehyde exposure in rat %K Blood urea nitrogen %K Formaldehyde %K Rats %K Vitamin E %R 10.22034/HBB.2018.27 %X In this study, effect of vitamin E on kidney after exposure to formaldehyde was evaluated. 24 adult male wistar rats divided randomly in three groups: control, formaldehyde (E1), vitamin E and formaldehyde (E2). After two weeks rats were sacrificed, and 5 ml of blood was taken from their heart. Blood urea nitrogen (BUN) and creatinine concentrations were measured. BUN concentration was significantly increased in E1 (P=0.03) and E2 groups (P=0.02) compare with control group. There were no significant differences in creatinine levels between groups (p=0.11). The results showed that vitamin E probably protect kidney against formaldehyde alterations in rat. It may be possible to use vitamin E when increasing blood urea concentrations to restore urea plasma balance and prevent kidney damage. %U https://www.healthbiotechpharm.org/article_133480_0dabd9b81143f3dd01a350af5330acf4.pdf