In silico evaluation of surface-exposed proteins of severe acute respiratory syndrome coronavirus 2 to propose a multi-epitope vaccine candidate
Volume 4, Issue 4 , March 2021, , Pages 51-72

https://doi.org/10.22034/HBB.2021.06

Abstract
  The novel Coronavirus disease 2019 caused a global outbreak therefore a promising vaccine is needed to combat it. In this study, the Spike (S) glycoprotein, Membrane (M) protein, and Envelope (E) protein have been tested as putative vaccine candidates. It was demonstrated that the second protrusion part ...  Read More

Drug repurposing against COVID-19 by GWAS
Volume 4, Issue 1 , June 2020, , Pages 1-6

https://doi.org/10.22034/HBB.2020.01

Abstract
  This note is prepared by the authors of a recent publication on shared genetic architecture of drug response based on summary statistics from genome-wide association studies (GWAS) to propose a drug repurposing approach for the treatment of coronavirus COVID-19. The authors proposed that in silico studies ...  Read More

In silico docking of matrix metalloproteinase inhibitors of Hemiscorpius Lepturus to human matrix metalloproteinases - opportunities for novel natural therapeutics
Volume 3, Issue 2 , September 2019, , Pages 16-39

https://doi.org/10.22034/HBB.2019.15

Abstract
  Hemiscorpius Lepturus is one of the most dangerous scorpion species in Iran. Four metalloproteinase inhibitors were detected in the transcriptome of venom gland of H.lepturus (HLMetInhibit1, HLMetInhibit2, HLMetInhibit3 and HLMetInhibit4). Their secondary and 3D structures were predicted using Iterative ...  Read More