Medicinal sciences
The comparison and analysis among clinical studies of tissue engineering in knee cartilage defects

Ria Andreinie; Jeanne Adiwinata Adiwinata Pawitan

Volume 7, Issue 1 , July 2023, , Pages 1-21

  Treatment of cartilage damage is not satisfactory mainly due to cartilage nature that is avascular, so that its nutrition only depends on the diffusion process, which does not support regeneration. One of the new approaches for regeneration of injured cartilage that have a future is tissue engineering. ...  Read More

Aqueous extract of Nigella sativa L suppress proinflamatory cytokine gene expression
Volume 1, Issue 4 , March 2018, , Pages 72-82

  Due to the side effects of current therapies for osteoarthritis one of the alternative medicine is using herbal medicine such as Nigella sativa L. We examined that alcoholic extract of Nigella sativa (AENS) has an anti-inflammatory activity. Cells were activated with 100 ng/ml lipopolysaccharide for ...  Read More

The effect of Glycirrhiza globra on osteoarthritis, suppress TNF-a, IL-1b, Cox-2, iNOS gene expression and prostaglandin E2 and nitric oxide production in particular chondrocytes and monocyte/macrophages
Volume 1, Issue 2 , September 2017, , Pages 70-82

  In this study, we evaluated the effects of avocado soybean unsaponifiables (Glycirrhiza globra) on proinflammatory mediators in chondrocytes and monocyte/macrophage-like cells. Cells were activated with 20 ng/ml lipopolysaccharide (LPS) for 24 h and cell supernatants were analyzed for prostaglandin E2 ...  Read More