Biological sciences
EZH2 expression role in angiogenesis of prostate malignancy

Sanaz Kavoosi; Sanam Rezazadeh Chafjiri; Nastaran Asghari Moghaddam

Volume 7, Issue 3 , December 2023, , Pages 10-29

  The gene Enhancer of Zeste Homolog 2 (EZH2) is shown to be involved in the progression of the angiogenesis in cancer including prostate cancer, also it is a well-known enzyme catalytic subunit, initially acting as a histone methyltransferase, to prevent expressing gene by trimethylating lysine at the ...  Read More

Advantages of selected natural and synthetic materials as scaffolds in vascular tissue engineering

Helsy Junaidi; Jeanne Adiwinata Pawitan

Volume 6, Issue 3 , December 2022, , Pages 11-22

  The development of tissue engineering provides various opportunities to vascular tissue engineering. Scaffold plays an essential role in vascular tissue engineering. The selection of biomaterials used as scaffolds will determine the success of vascular tissue engineering. The structure of vascular system, ...  Read More

Specific signaling pathways and drugs play key role in regulation of angiogenesis
Volume 4, Issue 1 , June 2020, , Pages 7-37

  In this study, angiogenesis inducers and inhibitors and some important drugs are introduced. Abnormal angiogenesis can occur if the balance between inhibitory and inducible factors disappears. Angiogenesis inducers include EGF, FGF2, TGF-β, VEGF, G-CSF, HGF, TGF-α, IL-8, TNF-α and angiogenesis ...  Read More

Cytotoxicity, anti-adhesive and anti-angiogenic effects of Caspian Cobra snake (Naja oxiana) venom on human endothelial cells
Volume 1, Issue 1 , June 2017, , Pages 54-63

  Snake bite was known as one of the most important public health concerns world wild. Respiratory and cardiac problems and destruction of endothelium system occurs as a result of snake bite. Some proteins and peptides in snake venom have potential for drug discovery studies. According to the important ...  Read More