Biological sciences
EZH2 expression role in angiogenesis of prostate malignancy

Sanaz Kavoosi; Sanam Rezazadeh Chafjiri; Nastaran Asghari Moghaddam

Volume 7, Issue 3 , December 2023, , Pages 10-29

https://doi.org/10.22034/HBB.2023.21

Abstract
  The gene Enhancer of Zeste Homolog 2 (EZH2) is shown to be involved in the progression of the angiogenesis in cancer including prostate cancer, also it is a well-known enzyme catalytic subunit, initially acting as a histone methyltransferase, to prevent expressing gene by trimethylating lysine at the ...  Read More

Specific signaling pathways and drugs play key role in regulation of angiogenesis
Volume 4, Issue 1 , June 2020, , Pages 7-37

https://doi.org/10.22034/HBB.2020.02

Abstract
  In this study, angiogenesis inducers and inhibitors and some important drugs are introduced. Abnormal angiogenesis can occur if the balance between inhibitory and inducible factors disappears. Angiogenesis inducers include EGF, FGF2, TGF-β, VEGF, G-CSF, HGF, TGF-α, IL-8, TNF-α and angiogenesis ...  Read More