Biological sciences
Afrah Talib Abdullah; kadhim F Kadhim
Abstract
The objective of this study was to isolate and genetically identify keratinophilic fungi associated with humans, test their susceptibility to nystatin, and evaluate the effectiveness of Methanol Extract (ME) from chamomile flowers against these fungi. No cytotoxic effects were observed in the extract ...
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The objective of this study was to isolate and genetically identify keratinophilic fungi associated with humans, test their susceptibility to nystatin, and evaluate the effectiveness of Methanol Extract (ME) from chamomile flowers against these fungi. No cytotoxic effects were observed in the extract cytotoxicity assay using human blood solution. The antifungal activity of the chamomile extract varied among different fungal isolates and extract concentrations. The extract exhibited a strong inhibitory effect on fungal growth, depending on the type of fungal strain and concentration. Statistical analysis revealed significant differences between the effects of the extract and the conventional antifungal medication (nystatin) on specific fungi. GC/MS analysis of the chamomile extract identified several bioactive compounds, including flavonoids, phenolic compounds, and essential oils. The presence of these bioactive components in the extract likely contributes to its high antifungal activity against the tested fungal infections.
Abstract
In this study, four sites were chosen in the habitat of the plant which are located in Kashan. In order to complete phytochemical studies during flowering in each site, leaves were collected and after extraction of essential oils by simultaneous method of distillation and extraction using organic solvents, ...
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In this study, four sites were chosen in the habitat of the plant which are located in Kashan. In order to complete phytochemical studies during flowering in each site, leaves were collected and after extraction of essential oils by simultaneous method of distillation and extraction using organic solvents, an analytical chromatography connected to a mass spectrometer (GC/MS) was used to identify the ingredients of essential oils. The results of the efficiency of leaves showed in different sites that the highest quantity belonged to the samples taken from sites 2 and 4. Comparison of essential oil compounds showed that the main compounds identified in all the leaf samples from all sites were compounds such as hexadecanoic acid.