Abstract
Dracocephalum Kotschyi Boiss, is one of Dracocephalum species which has been used in traditional Iranian medicine with pharmacological and biological activities. The antioxidant properties and total flavonoid and phenolic contents of three different extracts of Dracocephalum Kotschyi Boiss were investigated. ...
Read More
Dracocephalum Kotschyi Boiss, is one of Dracocephalum species which has been used in traditional Iranian medicine with pharmacological and biological activities. The antioxidant properties and total flavonoid and phenolic contents of three different extracts of Dracocephalum Kotschyi Boiss were investigated. The antioxidant activity of the extracts was calculated using three different assay including DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (ferric reducing ability of plasma) and ABTS (2,2ʹ-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)). Among these extracts, the methanol extracts showed the highest radical scavenging activity 6.87±0.01 μmoL Trolox/g ferric reducing activity and the best activity in ABTS test (7.47±0.03 μmoL Trolox/g). The methanol extract of Dracocephalum Kotschyi showed also the highest total phenolic content 188.08±0.01 mg GAE/g, followed by ethyl acetate extract 95.58±0.01 mg GAE/g and also greatest total flavonoid content with 1037.00±0.01 mg quercetine equivalents/g. The results of this study showed that the potent antioxidant activity of Dracocephalum Kotschyi make use it as a natural antioxidant in food industries and other pharmaceutical purposes.
Abstract
Phytochemical investigation of the aerial parts of Artemisia kopetdaghensis led to isolation and characterization of 5 compounds including 9-Oxo-tournefortiolide (1), 2,6,10-Trimethyl-2,5-epidioxy-7,10-epoxydodeca-3,11-dien-5-acetoxy (2), 6-Demethoxy-5,7-dihydroxy-4'-O-methylcapillarisin (3), Eupatilin ...
Read More
Phytochemical investigation of the aerial parts of Artemisia kopetdaghensis led to isolation and characterization of 5 compounds including 9-Oxo-tournefortiolide (1), 2,6,10-Trimethyl-2,5-epidioxy-7,10-epoxydodeca-3,11-dien-5-acetoxy (2), 6-Demethoxy-5,7-dihydroxy-4'-O-methylcapillarisin (3), Eupatilin (4) and 5, 7, 5'-trihydroxy-6, 2´, 4´-trimethoxyflavone (5). The chemical structures of these compounds were identified by spectroscopic analysis. The antioxidant activities of the pure compounds were evaluated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays and also the antimicrobial capacity were tested against gram positive and gram negative bacteria and fungi using minimum inhibitory concentration (MIC) method.
