Strategies in design of antibodies for cancer treatment
Volume 5, Issue 3 , December 2021, , Pages 72-96

https://doi.org/10.22034/HBB.2021.24

Abstract
  Structural bioinformatics and computational methodologies facilitate antibodies design. The rational design is used to achieve a new function or adopt a new structure. Computer algorithms can systematically search amino acid sequences and select the best one. One of the important points of protein therapeutics ...  Read More

In silico docking of matrix metalloproteinase inhibitors of Hemiscorpius Lepturus to human matrix metalloproteinases - opportunities for novel natural therapeutics
Volume 3, Issue 2 , September 2019, , Pages 16-39

https://doi.org/10.22034/HBB.2019.15

Abstract
  Hemiscorpius Lepturus is one of the most dangerous scorpion species in Iran. Four metalloproteinase inhibitors were detected in the transcriptome of venom gland of H.lepturus (HLMetInhibit1, HLMetInhibit2, HLMetInhibit3 and HLMetInhibit4). Their secondary and 3D structures were predicted using Iterative ...  Read More