Biological sciences
The golden doses of anti CD3/CD28 microbeads plus IL-15 promote expansion of specific T cells in human cytomegalovirus adaptive immunotherapy

Arsalan Jalili; Nasser Aghdami; Abbas Hajifathali; Maryam Sayahinouri

Volume 7, Issue 1 , July 2023, , Pages 22-45

https://doi.org/10.22034/HBB.2023.09

Abstract
  In this study, the use of anti-CD3/CD28 magnetic microbeads and IL-15 in the culture of T lymphocytes in vitro had a significant role in the proliferation and cytotoxicity of these cells. Peripheral blood mononuclear cells of 6 (Cytomegalovirus) HCMV positive volunteers were harvested, then the pure ...  Read More

Biological sciences
Inflammation and Colorectal Cancer: The Bioinformatics Analysis of Multifunctional Role of Microbiota and Diet in Colorectal Cancer Development

Mohammad Ali Pahlevan Neshan; Payam Shahnazi Gerdehsang; Ahmad Bereimipour; Nazila Bostanshirin; Haniyeh Sadat Hosseininia; Kaykhosro Moridi; Amin Ebrahimi Sadrabadi; Arsalan Jalili

Volume 5, Issue 4 , March 2022, , Pages 1-25

https://doi.org/10.22034/HBB.2022.01

Abstract
  Chronic inflammation in colorectal cancer can result in the progression of tumorigenesis. Inflammation in the colorectal part of the body can be affected by microbiota, as well as an individual diet. These two factors play a critical role in cancer types related to the colon and rectum. This inflammation ...  Read More